On April 26, 2025, in Rosalia, Washington, Richard Hattan was injured in a DUI hit-and-run crash caused by Riley Maley, who was later arrested on charges including vehicular assault and DUI.

On April 26, 2025, in Pierce County, Washington, Breezy Brisbin, a 21-year-old mother, tragically lost her life in a motorcycle accident involving an allegedly intoxicated driver.

On April 26, 2025, Rachel Nalley was found unresponsive in her cell at the Oklahoma County Detention Center in Oklahoma City, Oklahoma, and was pronounced dead shortly after. Her death is under investigation as a homicide pending the medical examiner's report.

On April 25, 2025, in Waukegan, Illinois, 54-year-old Jerry Jackson was fatally struck by a vehicle at the intersection of Lewis Avenue and Harding Avenue.

On April 25, 2025, in Edwards County, Illinois, 22-year-old Jaxin Lee was fatally struck by a pickup truck while walking on Illinois Route 130.

Vincent Stuart, 71, of Fulton, Illinois, died in a concrete truck rollover accident on Interstate 80 in Bureau County, Illinois, on April 25, 2025. The incident remains under investigation.

Tawni Jahns, 39, of Richland, Washington, was injured in a fatal single-vehicle accident near Marlin, Washington, on April 25, 2025, which resulted in the death of driver Don "Chris" Terrell.

On April 25, 2025, in rural Lonoke County, Arkansas, David Fields sustained injuries in a fatal head-on collision that claimed the life of another driver.

Brandon Bridgman, 51, was injured in a fatal head-on collision on State Highway 15 in Lonoke County, Arkansas, on April 25, 2025, leaving one person deceased and two others hurt.

On April 25, 2025, in Oklahoma City, Oklahoma, inmate Clinton Pike died following an altercation at the Oklahoma County Detention Center.

On April 25, 2025, in La Grange, Illinois, Melissa and Brett Lane, parents of five, were killed in a seven-car crash.

On April 25, 2025, in Lewisville, Minnesota, a vehicle collision on Highway 30 resulted in four individuals sustaining non-life-threatening injuries, including Jeanette York.

On April 24, 2025, in Murray, Utah, UTA rail worker Juan Madrid was fatally injured in an auto-pedestrian accident involving driver Brandon Palma, who was arrested at the scene.

On April 24, 2025, in Edmond, Oklahoma, Officer Caleb Hodam was stabbed during a traffic stop by 22-year-old Ocean Hudson, who was arrested and charged; Hodam remains in stable condition at OU Medical Center.

On April 24, 2025, in Spokane, Washington, 78-year-old Mary Shockley was fatally struck by a vehicle while walking in the West Hills Neighborhood.

On April 24, 2025, Courtley Platson was injured in a multi-vehicle collision on Interstate 35 in Faribault, Minnesota.

Griffin Sommer, 29, of Marble Falls, Texas, died on April 23, 2025, from injuries sustained in an April 3 pedestrian accident on U.S. 281.

A tragic church bus crash in Sallisaw, Oklahoma, on April 23, 2025, has claimed the lives of 11-year-old Baylee Coachman and the bus driver, who died on April 28 from injuries sustained in the collision.

On April 23, 2025, a three-vehicle collision on Illinois Route 33 near Beecher City, Illinois, resulted in injuries to Jackie Bushue, 66, of Beecher City.

Torrance Bishop, a 39-year-old inmate, was found dead in his cell at the Athens-Clarke County Jail in Athens, Georgia, on April 22, 2025.