On September 5, 2025, Maria Sanchez-Romero of Wenatchee, Washington, sustained injuries in a head-on collision on U.S. Highway 97 near Blewett Pass. The crash occurred when a northbound Nissan Rogue crossed the center line and collided with a southbound semi-truck.

On September 5, 2025, Sheryl Faye Gillson of Pillager, Minnesota, sustained life-threatening injuries in a two-vehicle crash on Highway 210 at 33rd Avenue SW in Sylvan Township, Cass County.

In Centralia, Illinois, on September 5, 2025, Jesse Pigg was injured in a traffic collision at the intersection of McCord and Cherry Streets after another vehicle failed to yield. Both Jesse and his passenger were transported to the hospital with injuries.

In Rockford, Illinois, on September 5, 2025, 45-year-old Mark Gesswein was killed in a motorcycle crash allegedly caused by a vehicular pursuit initiated by Jose E. Olivencia III. Olivencia has been charged with First Degree Murder following the fatal incident.

In Tift County, Georgia on September 4, 2025, Adam Caseres was killed in a two-vehicle crash after his motorcycle was struck by a BMW at the intersection of GA-35 and Kell Road. Authorities report he died from his injuries while being transported to the hospital.

On September 4, 2025, Thomas Clarence Lenertz of Alexandria, Minnesota, sustained non-life-threatening injuries in a two-vehicle collision on Minnesota Highway 29 in Alexandria Township, Douglas County.

On September 4, 2025, Aron Ray Leavstrom of Owatonna, Minnesota, sustained non-life-threatening injuries in a two-vehicle crash on northbound Interstate 35 near Medford Township in Steele County.

On September 4, 2025, Liberty Borg, age 25, of Minneapolis, Minnesota, was fatally injured in a collision at the intersection of Penn Avenue and Olson Memorial Highway in Hennepin County.

On September 4, 2025, Marisa Ardys Casebolt, age 25, of Minneapolis, Minnesota, was fatally injured in a two-vehicle crash at the intersection of Penn Avenue and Olson Memorial Highway in Hennepin County.

On September 4, 2025, Cynthia Rettajo Hemphill of Grand Rapids, MN, sustained non-life-threatening injuries in a vehicle incident on Highway 65 in Cornish Township, Aitkin County, Minnesota.

In Springville, Utah on September 4, 2025, Matthew Daines was fatally struck by a truck after pushing his wife out of its path. Daines' actions during the fatal DUI incident have drawn widespread attention, and the driver, Travis McIntyre, is facing multiple charges.

On September 3, 2025, Jorge Martinez was killed in Sunnyside, Washington, after being struck by a vehicle on I-82 in a suspected DUI crash.

Andre Champagne of Tulsa, Oklahoma, died following a two-vehicle crash on September 3, 2025, near the intersection of 71st Street and Yale Avenue.

On September 3, 2025, Dwane Sukert of Port Angeles, Washington, was killed in a semi-truck crash on Interstate 90 in North Bend, WA, following a tire blowout incident.

In Brockport, New York on September 3, 2025, Reginald Russell was found deceased following a high-speed police chase that ended when a stolen U-Haul crashed into the Erie Canal. Russell was a passenger in the vehicle driven by Ryan Armstrong, who now faces manslaughter charges.

In St. George, Utah on September 2, 2025, 22-year-old Jordan Konanui Kong died after falling from a fifth-floor balcony at Utah Tech University. Authorities are continuing to investigate the circumstances surrounding the incident.

In St. George, Utah on September 2, 2025, Jeffry and Catherine Gray were killed in a head-on collision caused by a wrong-way driver on I-15. The crash also resulted in a third fatality and two non-life-threatening injuries.

In Austin, Texas on September 2, 2025, Sheyla Mascorro died in a fatal Labor Day crash involving an intoxicated driver. Mascorro was pronounced dead at the scene, and the driver now faces charges of intoxication manslaughter.

On September 2, 2025, Stephen Hummel, age 72, sustained injuries in a collision between his motorcycle and a pickup truck at the intersection of Fourth Street NW and Seventh Avenue NW in Austin, Minnesota. The incident remains under investigation by local authorities.

On September 2, 2025, Aiden Riggins of Orleans, Massachusetts, sustained serious injuries in a head-on collision on Route 6 in Wellfleet.